Cissus Quadrangularis Extract

Ketosterones/Cissus Extract

Description-

Cissus Quadrangularis  is a succulent vine of India. It is one of the most commonly used medicinal plants in India, and is also used in traditional African and Ayurvedic medicine. All parts of the plant are used for medicine.

Active Ingredient : Ketosterones 1.5%, Ketosterones 2% & Ketosterones 2.5% , 3-Ketosterones 10%

Common Name : Veld Grape

Chemical Constituents and Components : Main chemical constituents are tetracyclic triterpenoids, onocer-7-ene-3alpha, 21 beta-diol and onocer-7-ene-3beta, 21 alpha-diol and two steriodal principles I and II, alpha-sitosterol, delta-amyrin

Uses-

Cissus Quadrangularis extract is used for obesity, diabetes, a cluster of heart disease risk factors called “metabolic syndrome,” and high cholesterol. It has also been used for bone fractures, weak bones (osteoporosis), scurvy, cancer, upset stomach, hemorrhoids, peptic ulcer disease (PUD), painful menstrual periods, asthma, malaria, and pain. Cissus Quadrangularis' extract is also used in bodybuilding supplements as an alternative to anabolic steroids.

Using a specific Cissus Quadrangularis extract (Calzbone, Verdure Sciences) to the skin improves fracture healing in some people. It is unclear is the effects of this product are due to Cissus Quadrangularis or the other ingredients in this product, which include calcium, vitamin D, and boswelia. By mouth twice daily taking Cissus Quadrangularis's extract improve hemorrhoid symptoms for 7 days. Taking a specific Cissus Quadrangularis's extract reduces weight in obese and overweight people.

Action :
Ketosterones :
1. It acts as antagonists to the glucocorticoid receptor and promote good bone health.
2. It shows anabolic steroid properties for healing of fracture.
3. It increases intramuscular creatinine levels.
4. It blocks the muscle damaging effect of cortisol and leads to the formation of new muscles.
5. It shows significant inhibition in DPPH free radical formation, superoxide radical production and lipid peroxide production in erythrocytes.
6. It shows sedative effect on central nervous system.
7. It protects gastric mucosa against ulceration by its antisecretory and cytoprotective property.
8. It mobilizes fibroblast and chondroblasts to an injured tissue and enhances regeneration.

Curing Diseases :

1. It is mainly used in treatment of fractured bones, asthma and cardiac problems.
2. It is anthelmintic, digestive and analgesic.
3. It is useful in eye and ear diseases and in irregular menstruation.
4. It is useful in colic, leprosy, ulcers, tumours and skin diseases.
5. It is helpful in back and spine problems.

Research Information : Cissus quadrangularis extract is used as dietary supplement or pharmaceutical composition. It provides prevention and treatment of osteo-health related disorders and diseases. (Ref. Use of the plant Cissus quadrangularis or its extracts for osteo-health including prevention or mitigation of degenerative disease, fracture healing and anabolic increase in osteo tissues, https://www.freepatentsonline.com/20050048141.html)