Veterinary Medicines Ivermectin CAS 70288-86-7 Quick details:Name:Ivermectin
Synonyms:Hyvermectin 70288-86-7
Alias:Amino Acids
CAS:70288-86-7
Style:Raw Material Steroid Powders
Export Markets:Global
Trademark:saichuang
Packing:1kg/Al Bag or as You RequiryS
tandard:usp high quality Glycine
Origin:China
Production Capacity:500kg/M
Model NO.: 70288-86-7
Appearance: Powder
Source: Organic Synthesis
Export Markets: Global
Origin: China
Production Capacity: 500 Metric Tons / Year
Product description: Ivermectin is a new kind of broad spectrum, high efficiency, low toxicity antibiotic drug resistant parasites, external parasite especially are good flooding kill nematodes and arthropods, widely used in cattle, sheep, horses, pigs, gastrointestinal nematodes, lung nematodes and parasitic arthropod, canine intestinal nematodes, ear mites, scabies mites, heart silk worm and microfilariae, gastrointestinal nematodes and external parasites, and poultry
Ivermectin is a semisynthetic, anthelmintic agent for oral administration. Ivermectin is derived from the avermectins, a class of highly active broad-spectrum anti-parasitic agents isolated from the fermentation products of Streptomyces avermitilis. Ivermectin is a mixture containing at least 90% 5-O-demethyl-22, 23-dihydroavermectin A1a and less than 10 % 5-O-demethyl-25-de(1-methylpropyl)-22, 23-dihydro-25-(1-methylethyl) avermectin A1b, generally referred to as 22, 23-dihydroavermectin B1a and B1b or H2B1a and H2B1b, respectively. The respective empirical formulas are C48H74O14 and C47H72O14, with molecular weights of 875.10 and 861.07, respectively.
Ivermectin is a white to yellowish-white, nonhygroscopic, crystalline powder with a melting point of about 155o C. It is insoluble in water but is freely soluble in methanol and soluble in 95% ethanol.
Use :
The product is an antibiotic agent, which is active against nematodes, insects and mites. Injection and tablet made from the product are active against gastrointestinal nematodes, hyproderma bovis, hyproderma lineatum, sheep nose bot, psoroptes ovis, sarcoptes scabiei var suis, sarcoptes ovis and the like, In addition, it is indicated for the treatment of endoparasites (nematodes such as rondworms and lungworms). The product may be formulated as an insecticide and miticide used in agriculture, which is efficacious against mites, diamondback worm, common cabbage worm, leafminers, psylla, nematodes and the like. Its main characteristics are as follows: It is efficacious against endo- and ecto-parasites only used once.
Storage
Sealed tightly and stored away from light in a cool and dry place.
Test item |
Specifications |
Description |
A white or yellowish-white crystalline powder |
Identification |
IR.HPLC |
Appearance of solution |
Clear and not ore intensely colored than reference solution BY7 |
Specific optical rotation |
-17--20° |
Related substances |
|
Impurity with a relative retention of 1.3 to 1.5 |
≤2.5% |
Any other impurity(apart from the 2 rincipal peaks) |
≤1.0% |
The sum of all related sub. |
≤5.0% |
Limit of ethanol |
≤5.0% |
Limit of formamide |
≤3.0% |
Heavy metals |
≤20ppm |
water |
≤1.0% |
Sulphated ash |
≤0.1% |
Assay(HPLC, base on drying) |
H2Bla/(H2Bla+H2BLB)≥90.0% |
102.0%)≥(H2Bla+H2Bla) )≥95.0% |