Citicoline sodium

Citicoline sodium

CAS 33818-15-4

MF C14H25N4NaO11P2

MW 510.31

Melting point:259-268°C (dec.)
alpha D20 +12.5° (c = 1.0 in H2O)
storage temp. 2-8°C
solubility H2O: 100mg/mL
form solid
color white
Water Solubility Soluble in water (100 mg/ml)

Citicoline is a nucleic acid derivatives, Geiger found that citicoline can restore brain injury in the animal experiments in 1956. Kennedy study confirmed that citicoline can make brain injury recovery in 1957. Takeda pharmaceutical company in Japan developed and produced it in 1961. It was registered in China in 1988, and is currently the best-selling drug among clinical brain diseases. It plays an important role in the synthesis of lecithin, by promoting the synthesis of lecithin and improving brain function. Experiments show that citicoline can enhance the levels of norepinephrine and dopamine in the central nervous system, thereby it can treat cerebrovascular disease, traumatic brain injury and cognitive impairment caused by various reasons, and there are no obvious side effects.

Citicoline sodium can enhance the function of brain stem reticular formation, especially the ascending reticular activating system associated with human consciousness; enhance the function of the pyramidal system; inhibit the function of the external system of the cone, and promotes the recovery of the function of the system. For the treatment of sequelae of traumatic brain injury and cerebral vascular accident caused by the nervous system, it can also be used in the treatment of Parkinson's disease, senile dementia has a certain effect; for the treatment of cardiovascular and cerebrovascular diseases; it also have a certain effect for anti-aging, improving learning and memory.

Application

1.Citicoline Sodium is a brain chemical that occurs naturally in the body.
2.As a medicine, Citicoline Sodium is taken by mouth as a supplement or given by IV or as a shot.
3.Citicoline Sodium is used for Alzheimer's disease and other types of dementia, head trauma, cerebrovascular disease such as stroke, age-related memory loss, Parkinson's disease, and glaucoma.
4.The main indications of Citicoline Sodium are acute traumatic brain injury and brain consciousness after the operation. Moreover, Citicoline Sodium can treat central nervous system dysfunction and unconsciousness caused by acute injury, paralysis agitans, tinnitus and nerve deafness, and poisoning caused by sleeping pills. In recent years, Citicoline Sodium is widely used in clinical for treatment of ischemic stroke, cerebral arteriosclerosis, multi-infarct dementia, Alzheimer's disease, and children viral encephalitis.