Quantity(Kilograms) | 1 - 50 | >50 |
Est. Time(day) | 2 | To be negotiated |
Melatonin, also known as N-acetyl-5-methoxy tryptamine, is a hormone that is produced by the pineal gland in animals and regulates sleep and wakefulness. Melatonin is also produced in plants where it functions as a first line of defense against oxidative stress.
In animals, melatonin is involved in the entrainment (synchronization) of the circadian rhythms including sleep-wake timing, blood pressure regulation, seasonal reproduction, and many others. Many of its biological effects in animals are produced through activation of melatonin receptors, while others are due to its role as an antioxidant, with a particular role in the protection of nuclear and mitochondrial DNA.
As a medicine, it is used for the treatment of insomnia; however, scientific evidence is insufficient to demonstrate a benefit in this area. Melatonin is sold over the counter in the United States, Canada and some European countries. In other countries, it may require a prescription or it may be unavailable.
Melatonin for sleep is by far its best known usage as a natural remedy. When it comes to sleep trouble, conventional medical treatment typically involves pharmaceutical drugs, but these medications frequently lead to long-term dependence and come with a laundry list of possible side effects. This is why many people want to find something more natural to help them have a more restful night's sleep.
2. Potential Treatment for Breast and Prostate Cancer
Several studies suggest that low melatonin levels may be associated with breast cancer risk. To determine melatonin's effectiveness at stopping tumor growth, one group of researchers evaluated the action of melatonin dosage on the growth of breast tumors in vitro (using human cancer cells) and in vivo (using mice). The researchers found that melatonin may inhibit tumor growth and cell production, as well as block the formation of new blood vessels in estrogen receptor-negative breast cancer models. This 2014 research shows melatonin's potential as a therapeutic agent for breast cancer.
3. Decreases Negative Menopause Symptoms
Melatonin supplements have been shown to improve sleep problems experienced during menopause. In a study of perimenopausal and menopausal women ages 42 to 62, within six months of a daily melatonin dosage, most of the women reported a general improvement of mood and a significant mitigation of depression. The findings of this study appear to demonstrate that melatonin supplementation among perimenopausal and menopausal women can lead to recovery of pituitary and thyroid functions toward a more youthful pattern of regulation. (
4. Heart Disease Helper
Multiple studies suggest that melatonin has heart-protective properties. Specifically, research shows that when it comes to cardiovascular health, melatonin has anti-inflammatory and antioxidant effects. It also can help lower blood pressure and cholesterol. It seems to have cardioprotective properties via its direct free radical scavenger activity. Overall, the protective abilities of melatonin may be able to help reduce and treat cardiovascular diseases.
5. Fibromyalgia and Chronic Pain Relief
Fibromyalgia symptoms include long-term and widespread pain in muscles and connective tissues, without any specific cause. A randomized, placebo-controlled study of 101 patients with fibromyalgia syndrome evaluated melatonin's effectiveness at reducing symptoms. It found that patients experienced a significant reduction in their symptoms when they took a melatonin dosage either alone or in conjunction with the antidepressant fluoxetine (Prozac).
6. Immune System Strengthener
Research is showing that melatonin has strong antioxidant effects and may help strengthen the immune system. A 2013 scientific review calls melatonin an "immune buffer" because it appears to act as a stimulant in an immunosuppressive condition, but it also behaves as an anti-inflammatory compound when there's an intensified immune response, like in the case of acute inflammation.
7. Eases Jet Lag
Jet lag is a temporary sleep disorder experienced by air travelers who rapidly travel by plane across multiple time zones. It happens as a result of the slow adjustment of the body clock to the destination time, which causes sleep and wakefulness to be out of sync with the new environment. Supplementing with melatonin may be able to help "reset" your sleep and wake cycle when you experience dreaded jet lag.
8. Better Outcomes for Autism in Children
Research has shown that melatonin can help children with developmental issues like autism. This is important, particularly with autism rates on the rise.
9. Helps Relieve Stress
Melatonin levels change when you are experiencing stress. Stress decreases melatonin concentrations at night and increases melatonin production during the day, which is due to the increase of cortisol, the stress hormone. Melatonin can help to relieve stress by controlling the level of stimulation experienced by the body.
If you are feeling anxious, melatonin helps to ease anxiety symptoms like daytime fatigue, drowsiness, insomnia and restlessness. It also promotes a calm mood and it supports brain function.
Healthlife Biotechnology Co., Ltd. is a pharmaceutical company mainly engaged in export of products including, without limitation, pharmaceutical raw materials both for vet and human, also Vitamins, Amino Acids, minerals, peptides, plant extract, feed and food additives.
Q1: Can I get some samples?
A: Yes, free samples are available for most of our products, you only need to pay the shipping cost.
Q2: How to confirm the quality before orders?
A: Two ways, either by free samples, or send us the detailed specifications, we will arrange the production as per your requirement.
Q3: What's your MOQ?
A: Normally 1 kg, but smaller quantity is also acceptable for some special products.
Q4: What's the delivery lead time?
A: 2-5 days after payment.
Q5: How about discount?
A: Mainly based on quantity, also some promotional products with special discount from time to time.
Q6: How to contact us?
A: IM: Trademanager, Skype, Whatsapp, Wechat; Call us directly or send us email.